TY - JOUR T1 - From Bedside to Bench: The Effect of Quality of Life on the Immune System and the Effect of the Immune System on Quality of Life JF - The Journal of Rheumatology JO - J Rheumatol SP - 1 LP - 1 DO - 10.3899/jrheum.110898 VL - 88 AU - BOULOS HARAOUI Y1 - 2011/11/01 UR - http://www.jrheum.org/content/88/1.abstract N2 - The chronic, disabling, and recurring nature of immune-mediated inflammatory diseases (IMID), accompanied by physical and psychological comorbidities, pain, and fatigue, can have a detrimental impact on a person’s quality of life (QOL). The degree by which the disease affects the QOL of an individual and his/her overall well-being is dependent on numerous factors, including age of onset, timing of diagnosis, socioeconomic status, cultural environment, and availability of personal and professional support. For example, children with inflammatory bowel disease (IBD) or juvenile idiopathic arthritis (JIA) often suffer from altered self-image, social isolation, family conflicts, and school absences, and may have difficulties maintaining social activities. The first year postdiagnosis appears to be an important time for a child to psychologically adjust to the possibility of … ER -