TY - JOUR T1 - Optimizing Use of Tumor Necrosis Factor Inhibitors in the Management of Immune-Mediated Inflammatory Diseases JF - The Journal of Rheumatology JO - J Rheumatol SP - 40 LP - 52 DO - 10.3899/jrheum.091464 VL - 85 AU - BRIAN BRESSLER AU - BOULOS HARAOUI AU - EDWARD KEYSTONE AU - ALESSANDRO SETTE Y1 - 2010/05/01 UR - http://www.jrheum.org/content/85/40.abstract N2 - The introduction of anti-tumor necrosis factor (TNF) therapies has dramatically improved the treatment of immune-mediated inflammatory diseases and provides treatment options for patients who do not respond to conventional disease-modifying antirheumatic drugs. However, the use of anti-TNF therapies still needs to be optimized. Dropoff rates, patients’ lack of response, and toxicity are issues that need to be addressed to render these therapies more effective for more patients. ER -