PT - JOURNAL ARTICLE AU - Jasvinder A. Singh AU - Michelle M. Dowsey AU - Michael Dohm AU - Susan M. Goodman AU - Amye L. Leong AU - Marieke M.J.H. Scholte Voshaar AU - Peter F. Choong TI - Achieving Consensus on Total Joint Replacement Trial Outcome Reporting Using the OMERACT Filter: Endorsement of the Final Core Domain Set for Total Hip and Total Knee Replacement Trials for Endstage Arthritis AID - 10.3899/jrheum.161113 DP - 2017 Jan 15 TA - The Journal of Rheumatology PG - jrheum.161113 4099 - http://www.jrheum.org/content/early/2017/01/05/jrheum.161113.short 4100 - http://www.jrheum.org/content/early/2017/01/05/jrheum.161113.full AB - Objective Discussion and endorsement of the OMERACT total joint replacement (TJR) core domain set for total hip replacement (THR) and total knee replacement (TKR) for endstage arthritis; and next steps for selection of instruments. Methods The OMERACT TJR working group met at the 2016 meeting at Whistler, British Columbia, Canada. We summarized the previous systematic reviews, the preliminary OMERACT TJR core domain set and results from previous surveys. We discussed preliminary core domains for TJR clinical trials, made modifications, and identified challenges with domain measurement. Results Working group participants (n = 26) reviewed, clarified, and endorsed each of the inner and middle circle domains and added a range of motion domain to the research agenda. TJR were limited to THR and TKR but included all endstage hip and knee arthritis refractory to medical treatment. Participants overwhelmingly endorsed identification and evaluation of top instruments mapping to the core domains (100%) and use of subscales of validated multidimensional instruments to measure core domains for the TJR clinical trial core measurement set (92%). Conclusion An OMERACT core domain set for hip/knee TJR trials has been defined and we are selecting instruments to develop the TJR clinical trial core measurement set to serve as a common foundation for harmonizing measures in TJR clinical trials.