PT  - JOURNAL ARTICLE
AU  - Matthew Laurence  Stoll
AU  - Yoginder Nath  Vaid
AU  - Saurabh Guleria
AU  - Timothy Beukelman
AU  - Peter Daniel  Waite
AU  - Randy Quentin  Cron
TI  - Magnetic Resonance Imaging Findings following Intraarticular Infliximab Therapy for Refractory Temporomandibular Joint Arthritis among Children with Juvenile Idiopathic Arthritis
AID  - 10.3899/jrheum.150308
DP  - 2015 Sep 01
TA  - The Journal of Rheumatology
PG  - jrheum.150308
4099  - http://www.jrheum.org/content/early/2015/08/26/jrheum.150308.short
4100  - http://www.jrheum.org/content/early/2015/08/26/jrheum.150308.full
AB  - Objective To evaluate the involvement of intraarticular (IA) infliximab (IFX) in the management of temporomandibular joint (TMJ) arthritis associated with juvenile idiopathic arthritis (JIA) that is refractory to systemic treatment and IA corticosteroid therapy. Methods Ours was a retrospective study of children with JIA who received IA IFX into the TMJ. The effectiveness of treatment on the progression of acute and chronic changes was assessed by a quantitative magnetic resonance imaging scoring system. Results Median acute and chronic scores worsened by 0.25 and 0.75, respectively. In multivariate analysis, worsening acute scores and passage of time predicted worsening of the chronic scores. Conclusion IA IFX allowed for progression of refractory TMJ arthritis in most but not all children with JIA.