TY - JOUR T1 - Comparison of 2 Dosages of Intraarticular Triamcinolone for the Treatment of Knee Arthritis: Results of a 12-week Randomized Controlled Clinical Trial JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.141630 SP - jrheum.141630 AU - Jan Willem Popma AU - Frank W. Snel AU - Cees J. Haagsma AU - Petra Brummelhuis-Visser AU - Hans G.J. Oldenhof AU - Job van der Palen AU - Mart A.F.J. van de Laar Y1 - 2015/08/01 UR - http://www.jrheum.org/content/early/2015/07/26/jrheum.141630.abstract N2 - Objective To determine whether a double dose of intraarticular triamcinolone acetonide is more effective for knee arthritis than a 40-mg dose. Methods In this 12-week randomized controlled clinical trial, 40 mg and 80 mg of intraarticular triamcinolone acetonide were compared in patients with knee arthritis. Evaluated variables included a Likert burden scale, visual analog scale pain scale, degree of arthritis activity, presence of swelling, and presence of functional limitation. Results Ninety-seven patients were randomized. No significant differences were observed between the groups regarding any outcomes. Conclusion An 80-mg dose of triamcinolone acetonide had no additional benefit compared with 40 mg as treatment for knee arthritis. Trial registration: Nederlands Trial Register; trial registration number: NTR2298. ER -