TY - JOUR T1 - Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.140956 SP - jrheum.140956 AU - Caroline J. Aalbers AU - Danielle M. Gerlag AU - Margriet J. Vervoordeldonk AU - Paul P. Tak AU - Robert B. Landewé Y1 - 2015/07/15 UR - http://www.jrheum.org/content/early/2015/07/10/jrheum.140956.abstract N2 - Objective To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis. Methods Evaluation of standardized response means (SRM), Guyatt effect size, and Spearman rank correlation coefficient in a randomized controlled trial investigating the effect of an intraarticular etanercept injection. Results The CCI showed a high SRM (1.68) and high Guyatt effect size (2.72). Both visual analog scale of pain and functionality had a moderate Guyatt effect size (2.06, 2.44) and high SRM (0.81, 0.97). Conclusion This study supports the use of the CCI as a single-joint assessment after single-joint intervention. Clinical trial registration: NTR-1210. ER -