@article {Aalbersjrheum.140956, author = {Caroline J. Aalbers and Danielle M. Gerlag and Margriet J. Vervoordeldonk and Paul P. Tak and Robert B. Landew{\'e}}, title = {Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index}, elocation-id = {jrheum.140956}, year = {2015}, doi = {10.3899/jrheum.140956}, publisher = {The Journal of Rheumatology}, abstract = {Objective To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis. Methods Evaluation of standardized response means (SRM), Guyatt effect size, and Spearman rank correlation coefficient in a randomized controlled trial investigating the effect of an intraarticular etanercept injection. Results The CCI showed a high SRM (1.68) and high Guyatt effect size (2.72). Both visual analog scale of pain and functionality had a moderate Guyatt effect size (2.06, 2.44) and high SRM (0.81, 0.97). Conclusion This study supports the use of the CCI as a single-joint assessment after single-joint intervention. Clinical trial registration: NTR-1210.}, issn = {0315-162X}, URL = {https://www.jrheum.org/content/early/2015/07/10/jrheum.140956}, eprint = {https://www.jrheum.org/content/early/2015/07/10/jrheum.140956.full.pdf}, journal = {The Journal of Rheumatology} }