TY - JOUR T1 - Is Disease Activity in Rheumatoid Arthritis during Pregnancy and after Delivery Predictive for Disease Activity in a Subsequent Pregnancy? JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.150565 SP - jrheum.150565 AU - Hilal Ince-Askan AU - Johanna M.W. Hazes AU - Radboud J.E.M. Dolhain Y1 - 2015/12/01 UR - http://www.jrheum.org/content/early/2015/11/25/jrheum.150565.abstract N2 - Objective To determine whether disease activity in women with rheumatoid arthritis (RA) in 1 pregnancy is predictive for disease activity in a subsequent pregnancy. Methods In the Pregnancy-induced Amelioration of Rheumatoid Arthritis study, there are prospective data on 27 patients who participated twice. Improvement and deterioration is determined by changes in the Disease Activity Score in 28 joints. Results Only 4 patients (14.8%) had comparable disease courses in both pregnancies, whereas treatment remained mostly similar. In contrast, a flare postpartum after the first pregnancy was predictive for a flare after the second pregnancy (p = 0.003). Conclusion RA disease course in following pregnancies cannot be predicted based upon previous pregnancies. However, a flare postpartum seems to predict subsequent flares. ER -