@article {Ottavianijrheum.141067, author = {S{\'e}bastien Ottaviani and Pierre-Antoine Juge and Aurore Aubrun and Elisabeth Palazzo and Philippe Dieud{\'e}}, title = {Sensitivity and Reproducibility of Ultrasonography in Calcium Pyrophosphate Crystal Deposition in Knee Cartilage: A Cross-sectional Study}, elocation-id = {jrheum.141067}, year = {2015}, doi = {10.3899/jrheum.141067}, publisher = {The Journal of Rheumatology}, abstract = {Objective To compare the ability to detect calcium pyrophosphate (CPP) crystals deposition (CPPD) in knee cartilage by ultrasonography (US) and radiography. Methods Patients with knee effusion were consecutively included and underwent radiography and US evaluation of knees. Diagnosis of CPPD was made by the identification of CPP crystals. Two blinded rheumatologists performed US assessment. Results We included 51 patients (25 with CPPD). US revealed hyperechoic spots in all 25 patients with CPPD (sensitivity 100\%, specificity 92.3\%), whereas radiography revealed CPPD in 16 (sensitivity 64\%, specificity 100\%; p \< 0.0001). Conclusion US of knees is more sensitive than radiography for CPPD diagnosis.}, issn = {0315-162X}, URL = {https://www.jrheum.org/content/early/2015/06/11/jrheum.141067}, eprint = {https://www.jrheum.org/content/early/2015/06/11/jrheum.141067.full.pdf}, journal = {The Journal of Rheumatology} }