RT Journal Article
SR Electronic
T1 Remission in Early Rheumatoid Arthritis -- A Comparison of New ACR/EULAR Remission Criteria to Established Criteria
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.111341
DO 10.3899/jrheum.111341
A1 Bindee Kuriya
A1 Ye Sun
A1 Gilles Boire
A1 Boulos Haraoui
A1 Carol Hitchon
A1 Janet E. Pope
A1 John C. Thorne
A1 Edward C. Keystone
A1 Vivian P. Bykerk
YR 2012
UL http://www.jrheum.org/content/early/2012/04/11/jrheum.111341.abstract
AB Objective To describe the frequency of remission in an early rheumatoid arthritis (ERA) cohort. Methods The frequency of remission was evaluated, based on 8 definitions including the Booleanbased American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria. Results Of 369 patients, remission at 12 months ranged from 18% according to the ACR/EULAR clinical trial criteria to 40% according to the 28-joint Disease Activity Score (DAS28) < 2.6. Higher tender joint count, swollen joint count, and physician global scores were seen for DAS28-based definitions, and patient global assessment (PtGA) scores were almost 5-fold higher for DAS28 remission. Conclusion Remission is achievable in ERA but its frequency differs according to the remission definition applied. Adoption of the new ACR/EULAR definition will limit the number classified as in remission, especially if the PtGA criteria are rated high for reasons other than inflammatory arthritis.