RT Journal Article
SR Electronic
T1 Construct Validity of the Modified Numeric Rating Scale of Patient Global Assessment in Psoriatic Arthritis
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.110919
DO 10.3899/jrheum.110919
A1 Ying-Ying Leung
A1 Kwok-Wah Ho
A1 Tracy-Yanner Zhu
A1 Lai-Shan Tam
A1 Emily Wailin Kun
A1 Edmund Kwok-Ming Li
YR 2012
UL http://www.jrheum.org/content/early/2012/03/10/jrheum.110919.abstract
AB Objective The construct validity of the patient global health assessment (PGA) in psoriatic arthritis (PsA) has not been analyzed, despite its common use. We evaluated the construct validity of a numeric rating scale (NRS) of the PGA in PsA. Methods Patients with PsA who fulfilled the ClASsification for Psoriatic ARthritis (CASPAR) criteria were recruited at a tertiary referral center. Demographic data were collected and PGA data were determined from administration of an 11-point NRS (0 to 10 points representing best to worst status). Convergent and discriminant validity were evaluated by correlation between PGA and clinical variables. Patients were grouped as having severe disease based on Disease Activity Score 28-joint count (DAS28) &gt; 5.1, Health Assessment Questionnaire (HAQ) &gt; 1.0, walking with aids, and social welfare- dependent. Patients were grouped as being in remission by DAS28 &lt; 2.6 and the Minimal Disease Activity Criteria. Known-group validity of PGA was evaluated. Results A total of 125 patients (52% men) were studied. Convergent validity revealed strong correlations of PGA with pain score, HAQ, and DAS28; and weak correlations with skin severity score, physician’s global assessment and morning stiffness. In multivariate analysis, PGA was associated with pain, physical function, mental function, and skin severity score. PGA distinguished different levels of severity well, as determined by comparison with different known groups with large effect sizes. Conclusion Judged on an NRS, the PGA had good construct validity and satisfactorily distinguished all levels of severity in PsA.