TY - JOUR T1 - Identification of the Clinical Features Distinguishing Psoriatic Arthritis and Fibromyalgia JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.110893 SP - jrheum.110893 AU - Antonio Marchesoni AU - Fabiola Atzeni AU - Antonio Spadaro AU - Ennio Lubrano AU - Giuseppe Provenzano AU - Alberto Cauli AU - Ignazio Olivieri AU - Daniela Melchiorre AU - Carlo Salvarani AU - Raffaele Scarpa AU - Piercarlo Sarzi-Puttini AU - Monica Montepaone AU - Giovanni Porru AU - Salvatore D'Angelo AU - Mariagrazia Catanoso AU - Luisa Costa AU - Maria Manara AU - Valentina Varisco AU - Laura Rotunno AU - Orazio De Lucia AU - Gabriele De Marco Y1 - 2012/01/15 UR - http://www.jrheum.org/content/early/2012/01/12/jrheum.110893.abstract N2 - Objective To identify the clinical features that can help to distinguish between psoriatic arthritis (PsA) and fibromyalgia (FM). Methods Our cross-sectional study was carried out in 10 Italian rheumatology centers between January and September 2009, and enrolled all consecutive patients with PsA and FM who agreed to participate. Standard clinical and laboratory data for PsA and FM were collected from all patients. Records were made of somatic symptoms, response to nonsteroidal antiinflammatory drugs (NSAID), self-evaluated pain, general health, disability, and responses to the Fibromyalgia Impact Questionnaire. Data were statistically analyzed by univariate and multivariate analyses, and receiver-operating characteristic curves. The analysis concentrated on the clinical features shared by the 2 conditions. Results Two hundred sixty-six patients with PsA (mean age 51.7 yrs; disease duration 10.2 yrs) and 120 patients with FM (mean age 50.2 yrs; disease duration 5.6 yrs) were evaluated. Univariate analysis showed that patients with FM had higher mean tender point and enthesitis scores, more somatic symptoms, and responded less to NSAID. Multivariate analysis showed that the presence of ≥ 6 FM-associated symptoms and ≥ 8 tender points was the best predictor of FM. Conclusion The shared clinical features of PsA and FM that had the greatest discriminating power for FM were the number of FM-associated symptoms and tender point count. ER -