@article {Jollyjrheum.091443, author = {Meenakshi Jolly and Simon A. Pickard and Rachel A. Mikolaitis and Roger A. Rodby and Winston Sequeira and Joel A. Block}, title = {LupusQoL-US Benchmarks for US Patients with Systemic Lupus Erythematosus}, elocation-id = {jrheum.091443}, year = {2010}, doi = {10.3899/jrheum.091443}, publisher = {The Journal of Rheumatology}, abstract = {Objective The LupusQoL-US instrument was recently validated in the US. We studied the benchmarks for a US patient cohort with systemic lupus erythematosus (SLE) and relevant demographic and disease correlates. Methods LupusQoL-US was administered to 185 patients with SLE. Demographic data (age, sex, ethnicity, marital status) and disease features (duration, disease activity and damage) were assessed simultaneously. Descriptive statistics were obtained. LupusQoL-US domain scores were calculated, and compared by sex, ethnicity, and marital status using nonparametric tests. Correlation between LupusQoL-US domains and age, disease duration, disease activity, and disease damage were obtained. Results Mean age of patients was 42.2 {\textpm} 14.5 years; 94\% of subjects were women. African American patients comprised 60\% of the study cohort. The most affected domains were Fatigue and Physical Health. The least affected was Intimate Relationships. Age correlated with Physical Health, Pain, and Body Image (r = 0.15{\textendash}0.18). Differences were observed based on sex and marital status, but not by ethnicity; there the LupusQoL-US correlated inversely with disease activity (r = {\textendash}0.001 to {\textendash}0.36) and damage (r = {\textendash}0.003 to {\textendash}0.40). Conclusion All domains of the LupusQoL-US based health related quality of life (HRQOL) were affected adversely. HRQOL varied by age, sex, and marital status in our SLE cohort.}, issn = {0315-162X}, URL = {https://www.jrheum.org/content/early/2010/08/10/jrheum.091443}, eprint = {https://www.jrheum.org/content/early/2010/08/10/jrheum.091443.full.pdf}, journal = {The Journal of Rheumatology} }