TY - JOUR T1 - Pattern of Disease Onset, Diagnostic Delay, and Clinical Features in Juvenile Onset and Adult Onset Ankylosing Spondylitis JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.090435 SP - jrheum.090435 AU - Salih Ozgocmen AU - Ozge Ardicoglu AU - Ayhan Kamanli AU - Arzu Kaya AU - Bekir Durmus AU - Kadir Yildirim AU - Ozlem Baysal AU - Ali Gur AU - Saliha Karatay AU - Zuhal Altay AU - Remzi Cevik AU - Akin Erdal AU - Yuksel Ersoy AU - Aysegul J. Sarac AU - Ibrahim Tekeoglu AU - Mahir Ugur AU - Kemal Nas AU - Kazim Senel AU - Hasan Ulusoy Y1 - 2009/11/02 UR - http://www.jrheum.org/content/early/2009/10/29/jrheum.090435.abstract N2 - Objective To assess the frequency of juvenile onset ankylosing spondylitis (JOAS) in Turkish patients with AS and to compare with adult onset AS (AOAS) in a cross-sectional study design. Methods A total of 322 patients were recruited from the joint database of 5 university hospitals in eastern Turkey. Results Patients with JOAS (n = 43, 13.4%) had significantly longer diagnostic delay (9.21 vs 5.08 yrs), less severe axial involvement and more prevalent uveitis (OR 2.92, 95% CI 1.25–6.79), and peripheral involvement at onset (OR 3.25, 95% CI 1.51–6.98, adjusted for current age; and OR 2.26, 95% CI 1.07–4.76, adjusted for disease duration). Patients with AOAS had higher radiographic scores and more restricted clinimetrics but similar functional limitations and quality of life. Conclusion JOAS and AOAS had distinctive courses and Turkish patients with AS had similar features compared to other Caucasian patient populations. ER -