%0 Journal Article %A Francesco G. De Rosa %A György Ábel %A Vincent Agnello %T Observations on Cryoglobulin Testing: II. The Association of Oligoclonal Mixed Cryoglobulinemia with Cirrhosis in Patients Infected with Hepatitis C Virus %D 2009 %R 10.3899/jrheum.090189 %J The Journal of Rheumatology %X Objective To determine whether a mixed cryoglobulin type correlated with cirrhosis in patients infected with hepatitis C virus (HCV). Methods We investigated the results of mixed cryoglobulin tests performed in the clinical laboratory on patients with and without HCV infection. Results A higher prevalence of oligoclonal cryoglobulins designated Type IIa was present in HCV-infected patients with cirrhosis than in those without cirrhosis. Conclusion An association of Type IIa cryoglobulins with cirrhosis in HCV-infected patients has not previously been reported. %U https://www.jrheum.org/content/jrheum/early/2009/06/15/jrheum.090189.full.pdf