%0 Journal Article %A Marie Feser %A Lezlie A. Derber %A Kevin D. Deane %A Dennis C. Lezotte %A Michael H. Weisman %A Jane H. Buckner %A Ted Mikuls %A James O’Dell %A Peter K. Gregersen %A V. Michael Holers %A Jill M. Norris %T Plasma 25,OH Vitamin D Concentrations Are Not Associated with Rheumatoid Arthritis (RA)-related Autoantibodies in Individuals at Elevated Risk for RA %D 2009 %R 10.3899/jrheum.080764 %J The Journal of Rheumatology %P jrheum.080764 %X Objective To evaluate the association between rheumatoid arthritis (RA)-related autoantibodies and plasma 25,OH vitamin D in subjects at risk for RA. Methods In 1210 subjects without RA, 76 were positive for anti-cyclic citrullinated peptide antibodies or for at least 2 rheumatoid factors (RF; by nephelometry: RF-IgM, RF-IgG, RF-IgA). 25,OH vitamin D was measured in these cases and 154 autoantibody-negative controls from this cohort. Results 25,OH vitamin D levels did not differ between cases and controls (adjusted OR 1.23, 95% CI 0.93–1.63). Conclusion Vitamin D concentrations are not associated with RA-related autoimmunity in unaffected subjects at increased risk for RA. %U https://www.jrheum.org/content/jrheum/early/2009/03/13/jrheum.080764.full.pdf