TY - JOUR T1 - Severe Sensory Neuronopathy in Primary Sjögren Syndrome Resulting in Charcot Arthropathy JF - The Journal of Rheumatology JO - J Rheumatol SP - 1449 LP - 1451 DO - 10.3899/jrheum.160137 VL - 43 IS - 7 AU - MAI NGUYEN AU - CHRISTINE A. PESCHKEN Y1 - 2016/07/01 UR - http://www.jrheum.org/content/43/7/1449.abstract N2 - To the Editor:Sjögren syndrome (SS), an autoimmune disorder affecting the exocrine glands, is known to have many extraglandular manifestations including peripheral neuropathy1. In the setting of an underlying neuropathy, progressive joint destruction is known as Charcot arthropathy.We present a case of a 68-year-old woman with known SS presenting with functional loss of the right arm. She had presented initially 15 years earlier with keratoconjunctivitis sicca, arthralgias, and complaints of numbness and tingling of the right arm and both hands, and a positive antinuclear antibody (ANA). A diagnosis of SS was made; however, the patient was subsequently lost to followup. She was re-referred with a 6-month history of right shoulder pain. Rheumatology assessment revealed a 15-year history of right arm numbness, keratoconjunctivitis sicca, xerostomia, arthralgias, and fatigue. On history she reported an insensate right arm for “many years,” as well as a recent decrease in right leg sensation. There were no additional connective tissue disease symptoms other than an intermittent facial rash. Her medical history was otherwise unremarkable and she was not taking any … Address correspondence to Dr. C.A. Peschken, Associate Professor, Departments of Internal Medicine and Community Health Sciences, Faculty of Health Sciences, University of Manitoba, RR149 Arthritis Centre, 800 Sherbrook St., Winnipeg, Manitoba R3A 1M4, Canada. E-mail: Christine.peschken{at}umanitoba.ca ER -