TY - JOUR T1 - Orbital Myositis and Primary Sjögren Syndrome JF - The Journal of Rheumatology JO - J Rheumatol SP - 1536 LP - 1537 DO - 10.3899/jrheum.141318 VL - 42 IS - 8 AU - FRANÇOIS-XAVIER DANLOS AU - FADELA DAOUED AU - RAPHAÈLE SEROR AU - XAVIER MARIETTE Y1 - 2015/08/01 UR - http://www.jrheum.org/content/42/8/1536.abstract N2 - To the Editor:In this report, we describe a new systemic manifestation associated with primary Sjögren syndrome (pSS): orbital myositis (OM). Considered a systemic disorder, pSS is primarily characterized by lymphocytic infiltration of exocrine glands, resulting in functional impairment of salivary and lacrymal glands. The inflammatory process, however, extends beyond the exocrine glands and can potentially affect any organ.A 40-year-old white man with pSS was admitted with diplopia. Since 2002, his disease manifested with sicca syndrome, polyarthralgia, antinuclear antibodies, and anti-SSA and -SSB antibodies, and lymphocytic sialadenitis (focus score of 1) associated with Hashimoto thyroiditis. He previously developed 2 neurological complications: aseptic meningoradiculitis following treatment with infliximab in 2002 (in the Trial of Remicade in Primary Sjögren’s Syndrome randomized clinical trial)1, and bilateral idiopathic sudden … Address correspondence to Dr. X. Mariette, Hôpitaux Universitaires Paris-Sud, Assistance Publique des Hôpitaux de Paris, Hôpital Bicêtre, Service de Rhumatologie, 78 rue du Général Leclerc, Le Kremlin Bicêtre 94275, France. E-mail: xavier.mariette{at}bct.aphp.fr ER -