TY - JOUR T1 - Knee Pain and a Prior Injury Are Associated with Increased Risk of a New Knee Injury: Data from the Osteoarthritis Initiative JF - The Journal of Rheumatology JO - J Rheumatol SP - 1463 LP - 1469 DO - 10.3899/jrheum.150016 VL - 42 IS - 8 AU - Jeffrey B. Driban AU - Grace H. Lo AU - Charles B. Eaton AU - Lori Lyn Price AU - Bing Lu AU - Timothy E. McAlindon Y1 - 2015/08/01 UR - http://www.jrheum.org/content/42/8/1463.abstract N2 - Objective. We explored whether knee pain or a history of knee injury were associated with a knee injury in the following 12 months.Methods. We conducted longitudinal knee-based analyses among knees in the Osteoarthritis Initiative. We included both knees of all participants who had at least 1 followup visit with complete data. Our first sets of exposures were knee pain (chronic knee symptoms and severity) at baseline, 12-month, 24-month, and 36-month visits. Another exposure was a history of injury that we defined as a self-reported injury at any time prior to baseline, 12-month, 24-month, or 36-month visit. The outcome was self-reported knee injury during the past year at 12-month, 24-month, 36-month, and 48-month visits. We evaluated the association between ipsilateral and contralateral knee pain or history of injury and a new knee injury within 12 months of the exposure using generalized linear mixed model for repeated binary outcomes.Results. A knee with reported chronic knee symptoms or ipsilateral or contralateral history of an injury was more likely to experience a new knee injury in the following 12 months than a knee without chronic knee symptoms (OR 1.84, 95% CI 1.57–2.16) or prior injury (prior ipsilateral knee injury: OR 1.81, 95% CI 1.56–2.09. Prior contralateral knee injury: OR 1.43, 95% CI 1.23–1.66).Conclusion. Knee pain and a history of injury are associated with new knee injuries. It may be beneficial for individuals with knee pain or a history of injury to participate in injury prevention programs. ER -