TY - JOUR T1 - Assessment of the New 2012 EULAR/ACR Clinical Classification Criteria for Polymyalgia Rheumatica: A Prospective Multicenter Study JF - The Journal of Rheumatology JO - J Rheumatol SP - 893 LP - 900 DO - 10.3899/jrheum.151103 VL - 43 IS - 5 AU - Gulsen Ozen AU - Nevsun Inanc AU - Ali Ugur Unal AU - Seda Bas AU - Gezmis Kimyon AU - Bunyamin Kisacik AU - Ahmet Mesut Onat AU - Sadiye Murat AU - Havva Keskin AU - Meryem Can AU - Alperen Mengi AU - Necati Cakir AU - Ayse Balkarli AU - Veli Cobankara AU - Neslihan Yilmaz AU - Ayten Yazici AU - Atalay Dogru AU - Mehmet Sahin AU - Ali Sahin AU - Kevser Gok AU - Soner Senel AU - Omer Nuri Pamuk AU - Sema Yilmaz AU - Ozun Bayindir AU - Kenan Aksu AU - Yonca Cagatay AU - Lutfi Akyol AU - Mehmet Sayarlioglu AU - Gozde Yildirim-Cetin AU - Sule Yasar-Bilge AU - Ilker Yagci AU - Sibel Zehra Aydin AU - Fatma Alibaz-Oner AU - Pamir Atagunduz AU - Haner Direskeneli Y1 - 2016/05/01 UR - http://www.jrheum.org/content/43/5/893.abstract N2 - Objective. To assess the performance of the new 2012 provisional European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) polymyalgia rheumatica (PMR) clinical classification criteria in discriminating PMR from other mimicking conditions compared with the previous 5 diagnostic criteria in a multicenter prospective study.Methods. Patients older than 50 years, presenting with new-onset bilateral shoulder pain with elevated acute-phase reactants (APR), were assessed for the fulfillment of the new and old classification/diagnostic criteria sets for PMR. At the end of the 1-year followup, 133 patients were diagnosed with PMR (expert opinion) and 142 with non-PMR conditions [69 rheumatoid arthritis (RA)]. Discriminating capacity, sensitivity, and specificity of the criteria sets were estimated.Results. Discriminating capacity of the new clinical criteria for PMR from non-PMR conditions and RA as estimated by area under the curve (AUC) were good with AUC of 0.736 and 0.781, respectively. The new criteria had a sensitivity of 89.5% and a specificity of 57.7% when tested against all non-PMR cases. When tested against all RA, seropositive RA, seronegative RA, and non-RA control patients, specificity changed to 66.7%, 100%, 20.7%, and 49.3%, respectively. Except for the Bird criteria, the 4 previous criteria had lower sensitivity and higher specificity (ranging from 83%–93%) compared with the new clinical criteria in discriminating PMR from all other controls.Conclusion. The new 2012 EULAR/ACR clinical classification criteria for PMR is highly sensitive; however, its ability to discriminate PMR from other inflammatory/noninflammatory shoulder conditions, especially from seronegative RA, is not adequate. Imaging and other modifications such as cutoff values for APR might increase the specificity of the criteria. ER -