RT Journal Article SR Electronic T1 Sensitivity and Reproducibility of Ultrasonography in Calcium Pyrophosphate Crystal Deposition in Knee Cartilage: A Cross-sectional Study JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 1511 OP 1513 DO 10.3899/jrheum.141067 VO 42 IS 8 A1 Sébastien Ottaviani A1 Pierre-Antoine Juge A1 Aurore Aubrun A1 Elisabeth Palazzo A1 Philippe Dieudé YR 2015 UL http://www.jrheum.org/content/42/8/1511.abstract AB Objective. To compare the ability to detect calcium pyrophosphate (CPP) crystals deposition (CPPD) in knee cartilage by ultrasonography (US) and radiography.Methods. Patients with knee effusion were consecutively included and underwent radiography and US evaluation of knees. Diagnosis of CPPD was made by the identification of CPP crystals. Two blinded rheumatologists performed US assessment.Results. We included 51 patients (25 with CPPD). US revealed hyperechoic spots in all 25 patients with CPPD (sensitivity 100%, specificity 92.3%), whereas radiography revealed CPPD in 16 (sensitivity 64%, specificity 100%; p < 0.0001).Conclusion. US of knees is more sensitive than radiography for CPPD diagnosis.