TY - JOUR T1 - CanVasc Recommendations for the Management of Antineutrophil Cytoplasm Antibody-associated Vasculitides JF - The Journal of Rheumatology JO - J Rheumatol SP - 97 LP - 120 DO - 10.3899/jrheum.150376 VL - 43 IS - 1 AU - Lucy McGeoch AU - Marinka Twilt AU - Leilani Famorca AU - Volodko Bakowsky AU - Lillian Barra AU - Susan M. Benseler AU - David A. Cabral AU - Simon Carette AU - Gerald P. Cox AU - Navjot Dhindsa AU - Christine S. Dipchand AU - Aurore Fifi-Mah AU - Michelle Goulet AU - Nader Khalidi AU - Majed M. Khraishi AU - Patrick Liang AU - Nataliya Milman AU - Christian A. Pineau AU - Heather N. Reich AU - Nooshin Samadi AU - Kam Shojania AU - Regina Taylor-Gjevre AU - Tanveer E. Towheed AU - Judith Trudeau AU - Michael Walsh AU - Elaine Yacyshyn AU - Christian Pagnoux AU - for The Canadian Vasculitis Research Network Y1 - 2016/01/01 UR - http://www.jrheum.org/content/43/1/97.abstract N2 - Objective. The Canadian Vasculitis research network (CanVasc) is composed of physicians from different medical specialties and researchers with expertise in vasculitis. One of its aims is to develop recommendations for the diagnosis and management of antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV) in Canada.Methods. Diagnostic and therapeutic questions were developed based on the results of a national needs assessment survey. A systematic review of existing non-Canadian recommendations and guidelines for the diagnosis and management of AAV and studies of AAV published after the 2009 European League Against Rheumatism/European Vasculitis Society recommendations (publication date: January 2009) until November 2014 was performed in the Medline database, Cochrane library, and main vasculitis conference proceedings. Quality of supporting evidence for each therapeutic recommendation was graded. The full working group as well as additional reviewers, including patients, reviewed the developed therapeutic recommendations and nontherapeutic statements using a modified 2-step Delphi technique and through discussion to reach consensus.Results. Nineteen recommendations and 17 statements addressing general AAV diagnosis and management were developed, as well as appendices for practical use, for rheumatologists, nephrologists, respirologists, general internists, and all other healthcare professionals more occasionally involved in the management of patients with AAV in community and academic practice settings.Conclusion. These recommendations were developed based on a synthesis of existing international guidelines, other published supporting evidence, and expert consensus considering the Canadian healthcare context, with the intention of promoting best practices and improving healthcare delivery for patients with AAV. ER -