RT Journal Article SR Electronic T1 Development and Preliminary Validation of a Digital Overlay-based Learning Module for Semiquantitative Evaluation of Magnetic Resonance Imaging Lesions in Osteoarthritis of the Hip JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 232 OP 238 DO 10.3899/jrheum.141574 VO 43 IS 1 A1 Walter P. Maksymowych A1 Meaghan Pitts A1 Matthew J. Budak A1 David Gracey A1 Robert G. Lambert A1 David McDougall A1 Marcus Pianta A1 Winston J. Rennie A1 Stephanie Wichuk A1 Naomi Winn A1 Jacob L. Jaremko YR 2016 UL http://www.jrheum.org/content/43/1/232.abstract AB Objective. To develop and validate a knowledge transfer (KT) module aimed at enhancing feasibility and reliability of semiquantitative assessment of bone marrow lesions (BML) and synovitis-effusion using the Hip Inflammation Magnetic Resonance Imaging Scoring System (HIMRISS).Methods. Three radiologists naive to the HIMRISS method reviewed the manuscript describing the method and then scored MRI scans from 16 patients with hip OA obtained at baseline and 8 weeks after intraarticular injection of corticosteroid. Readers then reviewed a KT module comprising an instructional presentation and 8 reference DICOM (digital imaging and communications in medicine) cases scored by 3 readers with expertise in the HIMRISS method, and then used electronic overlay software to score scans from 23 patients with OA. The same format was followed with a second group of 3 readers naive to HIMRISS using a KT module revised to incorporate the overlay with a Web-based DICOM viewer to enhance feasibility. Interobserver reliability was assessed with the intraclass correlation coefficient (ICC).Results. In both exercises, reliability for baseline scores was excellent for femoral BML, very good for acetabular BML, and good for synovitis-effusion (overall ICC = 0.91, 0.89, 0.62, respectively) even without prior calibration using the KT module. However, reliability for detecting change was substantially worse than for expert readers, especially for acetabular BML and synovitis-effusion (overall ICC = 0.59 vs 0.19, and 0.42 vs 0.25, respectively). Reliability improved for detection of change in these lesions, especially after reader calibration with the revised KT module.Conclusion. Development and validation of a systematic method for KT may enhance external validation of certain imaging instruments.