RT Journal Article
SR Electronic
T1 Imaging as an Outcome Measure in Gout Studies: Report from the OMERACT Gout Working Group
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2460
OP 2464
DO 10.3899/jrheum.141164
VO 42
IS 12
A1 Rebecca Grainger
A1 Nicola Dalbeth
A1 Helen Keen
A1 Laura Durcan
A1 N. Lawrence Edwards
A1 Fernando Perez-Ruiz
A1 Cesar Diaz-Torne
A1 Jasvinder A. Singh
A1 Dinesh Khanna
A1 Lee S. Simon
A1 William J. Taylor
YR 2015
UL http://www.jrheum.org/content/42/12/2460.abstract
AB Objective. The gout working group at the Outcome Measures in Rheumatology (OMERACT) 12 meeting in 2014 aimed to determine which imaging modalities show the most promise for use as measurement instruments for outcomes in studies of people with chronic gout and to identify the key foci for future research about the performance of these imaging techniques with respect to the OMERACT filter 2.0.Methods. During the gout session, a systematic literature review of the data addressing imaging modalities including plain radiography (XR), conventional computed tomography (CT), dual-energy computed tomography (DECT), magnetic resonance imaging (MRI), and ultrasound (US) and the fulfillment of the OMERACT filter 2.0 was presented.Results. The working group identified 3 relevant domains for imaging in gout studies: urate deposition (tophus burden), joint inflammation, and structural joint damage.Conclusion. The working group prioritized gaps in the data and identified a research agenda.