RT Journal Article
SR Electronic
T1 Comparison of 2 Dosages of Intraarticular Triamcinolone for the Treatment of Knee Arthritis: Results of a 12-week Randomized Controlled Clinical Trial
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1865
OP 1868
DO 10.3899/jrheum.141630
VO 42
IS 10
A1 Jan Willem Popma
A1 Frank W. Snel
A1 Cees J. Haagsma
A1 Petra Brummelhuis-Visser
A1 Hans G.J. Oldenhof
A1 Job van der Palen
A1 Mart A.F.J. van de Laar
YR 2015
UL http://www.jrheum.org/content/42/10/1865.abstract
AB Objective. To determine whether a double dose of intraarticular triamcinolone acetonide is more effective for knee arthritis than a 40-mg dose.Methods. In this 12-week randomized controlled clinical trial, 40 mg and 80 mg of intraarticular triamcinolone acetonide were compared in patients with knee arthritis. Evaluated variables included a Likert burden scale, visual analog scale pain scale, degree of arthritis activity, presence of swelling, and presence of functional limitation.Results. Ninety-seven patients were randomized. No significant differences were observed between the groups regarding any outcomes.Conclusion. An 80-mg dose of triamcinolone acetonide had no additional benefit compared with 40 mg as treatment for knee arthritis. Trial registration: Nederlands Trial Register; trial registration number: NTR2298.