TY - JOUR T1 - Comprehensive Treatment of Psoriatic Arthritis: Managing Comorbidities and Extraarticular Manifestations JF - The Journal of Rheumatology JO - J Rheumatol SP - 2315 LP - 2322 DO - 10.3899/jrheum.140882 VL - 41 IS - 11 AU - Alexis Ogdie AU - Sergio Schwartzman AU - Lihi Eder AU - Ajesh B. Maharaj AU - Devy Zisman AU - Siba P. Raychaudhuri AU - Soumya M. Reddy AU - Elaine Husni Y1 - 2014/11/01 UR - http://www.jrheum.org/content/41/11/2315.abstract N2 - Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis that can lead to decreased health-related quality of life and permanent joint damage leading to functional decline. In addition to joint and skin manifestations, both psoriasis and PsA are associated with numerous comorbidities and extraarticular/cutaneous manifestations, which may influence the physician’s choice of therapy. The objectives of this review are (1) to identify comorbidities in patients with PsA based on the available evidence; (2) to examine the effects of these comorbidities or extraarticular/cutaneous manifestation on the management of patients with PsA as well as the selection of therapy; and (3) to highlight research needs around comorbidities and treatment paradigms. This review is part of a treatment recommendations update initiated by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA). ER -