TY - JOUR T1 - Comparison of Labial Minor Salivary Gland Biopsies from Childhood Sjögren Syndrome and Age-matched Controls JF - The Journal of Rheumatology JO - J Rheumatol SP - 1178 LP - 1182 DO - 10.3899/jrheum.131511 VL - 41 IS - 6 AU - Naoto Yokogawa AU - Scott M. Lieberman AU - Faizan Alawi AU - Sharon Bout-Tabaku AU - Marta Guttenberg AU - David D. Sherry AU - Frederick B. Vivino Y1 - 2014/06/01 UR - http://www.jrheum.org/content/41/6/1178.abstract N2 - Objective. To determine an appropriate focus score cutoff for childhood Sjögren syndrome (SS). Methods. Labial salivary gland tissue from specimens from children with SS and age-matched controls was retrospectively identified and reviewed by a blinded oral pathologist. Results. The presence of any focal sialadenitis (focus score > 0 foci/4 mm2) was common among childhood SS samples but present in only 1 of 8 control samples. Conclusion. The presence of any focal lymphocytic sialadenitis in minor labial salivary gland tissue is suggestive of childhood SS and should be included in future childhood SS-specific diagnostic or classification criteria. ER -