TY - JOUR T1 - American College of Rheumatology Criteria at Inception, and Accrual over 5 Years in the SLICC Inception Cohort JF - The Journal of Rheumatology JO - J Rheumatol SP - 875 LP - 880 DO - 10.3899/jrheum.130704 VL - 41 IS - 5 AU - Murray B. Urowitz AU - Dafna D. Gladman AU - Dominique Ibañez AU - Jorge Sanchez-Guerrero AU - Juanita Romero-Diaz AU - Caroline Gordon AU - Sang-Cheol Bae AU - Anne E. Clarke AU - Sasha Bernatsky AU - Paul R. Fortin AU - John G. Hanly AU - David Isenberg AU - Anisur Rahman AU - Daniel J. Wallace AU - Ellen Ginzler AU - Michelle Petri AU - Ian N. Bruce AU - Joan T. Merrill AU - Ola Nived AU - Gunnar Sturfelt AU - Mary Anne Dooley AU - Graciela S. Alarcón AU - Barri Fessler AU - Kristjan Steinsson AU - Rosalind Ramsey-Goldman AU - Asad Zoma AU - Munther Khamashta AU - Susan Manzi AU - Ronald van Vollenhoven AU - Manuel Ramos-Casals AU - Cynthia Aranow AU - Thomas Stoll Y1 - 2014/05/01 UR - http://www.jrheum.org/content/41/5/875.abstract N2 - Objective. To determine the frequency of each American College of Rheumatology (ACR) criterion met at time of enrollment, and the increase in each of the criteria over 5 years. Methods. In 2000 the Systemic Lupus International Collaborating Clinics (SLICC) recruited an international inception cohort of patients with systemic lupus erythematosus (SLE; ≥ 4 ACR criteria) who were followed at yearly intervals according to a standard protocol. Descriptive statistics were used to assess the total and cumulative number of ACR criteria met at each visit. Regression models were done to compare the increase of individual and cumulative criteria as a function of race/ethnicity group, and sex. Results In all, 768 patients have been followed for a minimum of 5 years. Overall, 59.1% of the patients had an increase in the number of ACR criteria they met over the 5-year period. The mean number of ACR criteria met at enrollment was 5.04 ± 1.13 and at year 5 was 6.03 ± 1.42. At enrollment, nonwhite patients had a higher number of ACR criteria (5.19 ± 1.23) than white patients. The total number of criteria increased in both white and nonwhite ethnicities, but increased more among whites. Males had a slightly lower number of criteria at enrollment compared to females and males accrued fewer criteria at 5 years. Conclusion. In this international inception cohort of SLE patients with at least 4 ACR criteria at entry, there was an accumulation of ACR criteria over the following 5 years. The distribution of criteria both at inception and over 5 years is affected by sex and ethnicity. ER -