PT - JOURNAL ARTICLE AU - Ryan Ng AU - Sasha Bernatsky AU - Elham Rahme TI - Observation Period Effects on Estimation of Systemic Lupus Erythematosus Incidence and Prevalence in Quebec AID - 10.3899/jrheum.121215 DP - 2013 Aug 01 TA - The Journal of Rheumatology PG - 1334--1336 VI - 40 IP - 8 4099 - http://www.jrheum.org/content/40/8/1334.short 4100 - http://www.jrheum.org/content/40/8/1334.full SO - J Rheumatol2013 Aug 01; 40 AB - Objective. To determine how duration of observation affects estimation of incidence and prevalence of systemic lupus erythematosus (SLE). Methods. SLE incidence and prevalence estimates from data periods as brief as 3 years (2001–2003) were compared to estimates from a 15-year period (1989–2003). Results. The 15-year period incidence was 5.6/100,000 (95% CI 5.0–6.1) and the prevalence was 59.1/100,000 (95% CI 57.4–60.8). When a 3-year period was used, incidence was overestimated by 238.1% and prevalence underestimated by 66.0%. Conclusion. SLE incidence and prevalence estimates vary considerably according to the observation period; more than 5 years of data is likely required.