RT Journal Article
SR Electronic
T1 Nail Disease in Psoriatic Arthritis: Distal Phalangeal Bone Edema Detected by Magnetic Resonance Imaging Predicts Development of Onycholysis and Hyperkeratosis
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 841
OP 843
DO 10.3899/jrheum.111118
VO 39
IS 4
A1 NICOLA DALBETH
A1 KAREN PUI
A1 MARIA LOBO
A1 ANTHONY DOYLE
A1 PETER B. JONES
A1 WILLIAM J. TAYLOR
A1 FIONA M. McQUEEN
YR 2012
UL http://www.jrheum.org/content/39/4/841.abstract
AB Objective. To examine the association between magnetic resonance imaging (MRI) features of distal phalanx (DP) disease and the progression of nail pathology in psoriatic arthritis (PsA). Methods. Clinical nail assessment and hand MRI scans were done on 34 patients with PsA. Twenty patients had repeat nail assessments after 1 year. Results. Nails with onycholysis and hyperkeratosis at baseline were more likely to have corresponding DP bone erosion and proliferation on MRI. DP bone edema on baseline MRI was associated with development of onycholysis and hyperkeratosis in corresponding nails. Conclusion. Our data suggest that DP inflammation is central in the development of psoriatic nail disease.