TY - JOUR T1 - Beneficial Effect of N-acetylcysteine on Antineutrophil Cytoplasmic Antibody-associated Vasculitis JF - The Journal of Rheumatology JO - J Rheumatol SP - 186 LP - 186 DO - 10.3899/jrheum.111025 VL - 39 IS - 1 AU - SE JIN PARK AU - KI SOO PAI AU - JI HONG KIM AU - JAE IL SHIN Y1 - 2012/01/01 UR - http://www.jrheum.org/content/39/1/186.2.abstract N2 - To the Editor:We read with interest the recent contribution by Drs. Fernández-Fernández and Sesma1. They introduced 2 significant studies: the IFIGENIA trial (Idiopathic Pulmonary Fibrosis International Group Exploring N-Acetylcysteine I Annual study)2 and the study by Guilpain, et al3 showing that antimyeloperoxidase (MPO) antibodies generated a reactive oxygen species that was highly harmful to endothelial cells, and that N-acetylcysteine (NAC) … Address correspondence to Dr. J. Shin, 250 Sungsanno, Seodaemun-gu, CPO Box 8044, Department of Pediatrics, Yonsei University College of Medicine, Seoul 120-752, Korea. E-mail: shinji{at}yuhs.ac ER -