TY - JOUR T1 - Thrombovascular Events Affect Quality of Life in Patients with Systemic Lupus Erythematosus JF - The Journal of Rheumatology JO - J Rheumatol SP - 1017 LP - 1019 DO - 10.3899/jrheum.101054 VL - 38 IS - 6 AU - AMARIS K. BALITSKY AU - VALENTINA PEEVA AU - JIANDONG SU AU - ELAHEH AGHDASSI AU - ERIC YEO AU - DAFNA D. GLADMAN AU - MURRAY B. UROWITZ AU - PAUL R. FORTIN Y1 - 2011/06/01 UR - http://www.jrheum.org/content/38/6/1017.abstract N2 - Objective. To compare health-related quality of life (HRQOL) of patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) with and without previous thrombovascular events (TE). Methods. The Medical Outcomes Study Short-Form 36 (SF-36) was used to assess HRQOL in 5 patient groups: (1) primary APS (PAPS; n = 35); (2) APS associated to SLE (SAPS; n = 37); (3) SLE+TE without persistent positive antiphospholipid antibody (SLE+TE–aPL; n = 75); (4) SLE–TE+aPL (n = 71); and (5) SLE–TE–aPL (n = 608). Results. The data on both mental component summary and physical component summary (PCS) scores showed an impaired quality of life in all patient groups. Patients in the SLE+TE–aPL group had a lower PCS score compared to patients in the SLE–TE+aPL group. Conclusion. The combination of SLE and TE has a more negative influence on reported HRQOL, compared to having SLE or APS alone. ER -