PT  - JOURNAL ARTICLE
AU  - FRANCISCO JAVIER JIMÉNEZ-BALDERAS
AU  - GEMA FERNANDEZ-ARRIETA
AU  - ADOLFO CAMARGO-CORONEL
AU  - MIGUEL ÁNGEL AKE-UC
AU  - MIGUEL ANGEL VAZQUEZ-ZARAGOZA
AU  - ABRAHAM ZONANA-NACACH
AU  - LUIS ROBERTO SÁNCHEZ-GONZÁLEZ
AU  - RITA RIOS
AU  - FRANCISCO MARTINEZ-CASTRO
TI  - Uveitis in Adult Patients with Rheumatic Inflammatory Autoimmune Diseases at a Tertiary-care Hospital in Mexico City
AID  - 10.3899/jrheum.100015
DP  - 2011 Feb 01
TA  - The Journal of Rheumatology
PG  - 325--330
VI  - 38
IP  - 2
4099  - http://www.jrheum.org/content/38/2/325.short
4100  - http://www.jrheum.org/content/38/2/325.full
SO  - J Rheumatol2011 Feb 01; 38
AB  - Objective. Our aim is to describe the frequency of uveitis associated with rheumatic inflammatory autoimmune diseases (RIAD) in adult patients admitted to the Rheumatology Department at a tertiary-care hospital in Mexico City. We also describe the clinical features, seasonal distribution, treatment, and ocular complications associated with this disease. Methods. We reviewed 1332 charts of patients with RIAD and selected those that had a diagnosis of uveitis. We obtained the following data: age, sex, type of uveitis and relationship with diagnosis of RIAD, recurrences, seasonal distribution, treatment, and residual visual deficit. Results. We found 57 (4.27%) cases of uveitis in 1332 charts, including 38 men and 19 women (M:F ratio 2:1), aged 47 ± 16 years. Nongranulomatous acute anterior uveitis (NGAAU) comprised 90.52% of cases (52/57). In 64.91% of cases (37/57), uveitis preceded the diagnosis of RIAD by 12 ± 9 years, more frequently in winter (35.96%; p = NS). Uveitis was found in 40/93 patients with ankylosing spondylitis (AS), in 7/11 patients with relapsing polychondritis (RP), in 8/16 patients with Behçet’s disease, in 1/16 patients with polyarteritis nodosa, and in 1/590 patients with rheumatoid arthritis (RA). Ninety-six percent of the patients were treated with steroids. Upon a mean followup of 60 days (range 7–4745 days), reduction of visual acuity (≤ 20/200) was associated with recurrence of uveitis in 3/7 cases with AS, in 4/8 cases with Behçet’s disease, in 3/7 with RP, and in 1 case of uveitis and seronegative RA. Conclusion. NGAAU frequently precedes RIAD and is found predominately in men, with a tendency to occur in winter.