TY - JOUR T1 - Drs. Fisher and Cronstein reply JF - The Journal of Rheumatology JO - J Rheumatol SP - 1065 LP - 1065 DO - 10.3899/jrheum.091312 VL - 37 IS - 5 AU - MARK FISHER AU - BRUCE CRONSTEIN Y1 - 2010/05/01 UR - http://www.jrheum.org/content/37/5/1065.1.abstract N2 - To the Editor:We read with interest Ranganathan and McLeod’s comments and agree with their conclusions. We carried out our metaanalysis1 of the association of single-nucleotide polymorphisms (SNP) in the methylenetetrahydrofolate reductase (MTHFR) gene with methotrexate (MTX) toxicity because of the extremely … Address correspondence to Dr. Fisher. E-mail: markcfisher{at}gmail.com ER -