RT Journal Article SR Electronic T1 Estimating Indirect Costs in Primary Sjögren’s Syndrome JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 1010 OP 1015 DO 10.3899/jrheum.090734 VO 37 IS 5 A1 SIMON J. BOWMAN A1 YVAN ST. PIERRE A1 NURHAN SUTCLIFFE A1 DAVID A. ISENBERG A1 FIONA GOLDBLATT A1 ELIZABETH PRICE A1 JOHN HAMBURGER A1 ANDREA RICHARDS A1 SAAEHA RAUZ A1 MARIAN REGAN A1 SHIRLEY RIGBY A1 ADRIAN JONES A1 DIARMUID MULHERIN A1 ANN E. CLARKE YR 2010 UL http://www.jrheum.org/content/37/5/1010.abstract AB Objective. To estimate the indirect costs associated with primary Sjögren’s syndrome (pSS) compared with rheumatoid arthritis (RA) and community controls. Methods. Data were obtained from 84 women patients with pSS as part of a study to develop a systemic activity measure, from 87 consecutive women patients with RA attending a hospital clinic, and from 96 women community controls on a general practice list. A modified economic component of the Stanford Health Assessment Questionnaire was used to assess lost productivity. Results. Using a conservative model, the estimated total annual indirect costs (95% CI) were £7677 (£5560, £9794) for pSS, £10,444 (£8206, £12,681) for RA, and £892 (£307, £1478) for controls. Using a model that maximizes the estimates, the equivalent figures were £13,502 (£9542, £17,463), £17,070 (£13,112, £21,028), and £3382 (£2187, £4578), respectively. These were all significantly greater at p < 0.001 for patient groups than for the control group. Conclusion. pSS is associated with significantly increased indirect costs equivalent to 69%–83% of that for patients with RA. This needs to be taken into account when evaluating the overall economic consequences of pSS.