RT Journal Article
SR Electronic
T1 Psychological Correlates of Self-reported Disease Activity in Ankylosing Spondylitis
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 829
OP 834
DO 10.3899/jrheum.090476
VO 37
IS 4
A1 TAMAR F. BRIONEZ
A1 SHERVIN ASSASSI
A1 JOHN D. REVEILLE
A1 CHARLES GREEN
A1 THOMAS LEARCH
A1 LAURA DIEKMAN
A1 MICHAEL M. WARD
A1 JOHN C. DAVIS, Jr
A1 MICHAEL H. WEISMAN
A1 PERRY NICASSIO
YR 2010
UL http://www.jrheum.org/content/37/4/829.abstract
AB Objective. To investigate the role of psychological variables in self-reported disease activity in patients with ankylosing spondylitis (AS), while controlling for demographic and medical variables. Methods. Patients with AS (n = 294) meeting modified New York criteria completed psychological measures evaluating depression, resilience, active and passive coping, internality, and helplessness. Demographic, clinical, and radiologic data were also collected. Univariate and multivariate analyses were completed to determine the strength of the correlation of psychological variables with disease activity, as measured by the Bath AS Disease Activity Index (BASDAI). Results. In the multivariate regression analysis, the psychological variables contributed significantly to the variance in BASDAI scores, adding an additional 33% to the overall R-square beyond that accounted for by demographic and medical variables (combined R-square 18%). Specifically, arthritis helplessness and depression accounted for the most significant portion of the variance in BASDAI scores in the final model. Conclusion. Arthritis helplessness and depression accounted for significant variability in self-reported disease activity beyond clinical and demographic variables in patients with AS. These findings have important clinical implications in the treatment and monitoring of disease activity in AS, and suggest potential avenues of intervention.