TY - JOUR T1 - Observations on Cryoglobulin Testing: II. The Association of Oligoclonal Mixed Cryoglobulinemia with Cirrhosis in Patients Infected with Hepatitis C Virus JF - The Journal of Rheumatology JO - J Rheumatol SP - 1956 LP - 1957 DO - 10.3899/jrheum.090189 VL - 36 IS - 9 AU - FRANCESCO G. DE ROSA AU - GYÖRGY ÁBEL AU - VINCENT AGNELLO Y1 - 2009/09/01 UR - http://www.jrheum.org/content/36/9/1956.abstract N2 - Objective. To determine whether a mixed cryoglobulin type correlated with cirrhosis in patients infected with hepatitis C virus (HCV). Methods. We investigated the results of mixed cryoglobulin tests performed in the clinical laboratory on patients with and without HCV infection. Results. A higher prevalence of oligoclonal cryoglobulins designated Type IIa was present in HCV-infected patients with cirrhosis than in those without cirrhosis. Conclusion. An association of Type IIa cryoglobulins with cirrhosis in HCV-infected patients has not previously been reported. ER -