RT Journal Article SR Electronic T1 Observations on Cryoglobulin Testing: II. The Association of Oligoclonal Mixed Cryoglobulinemia with Cirrhosis in Patients Infected with Hepatitis C Virus JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 1956 OP 1957 DO 10.3899/jrheum.090189 VO 36 IS 9 A1 FRANCESCO G. DE ROSA A1 GYÖRGY ÁBEL A1 VINCENT AGNELLO YR 2009 UL http://www.jrheum.org/content/36/9/1956.abstract AB Objective. To determine whether a mixed cryoglobulin type correlated with cirrhosis in patients infected with hepatitis C virus (HCV). Methods. We investigated the results of mixed cryoglobulin tests performed in the clinical laboratory on patients with and without HCV infection. Results. A higher prevalence of oligoclonal cryoglobulins designated Type IIa was present in HCV-infected patients with cirrhosis than in those without cirrhosis. Conclusion. An association of Type IIa cryoglobulins with cirrhosis in HCV-infected patients has not previously been reported.