PT - JOURNAL ARTICLE AU - FRANCESCO G. DE ROSA AU - GYÖRGY ÁBEL AU - VINCENT AGNELLO TI - Observations on Cryoglobulin Testing: II. The Association of Oligoclonal Mixed Cryoglobulinemia with Cirrhosis in Patients Infected with Hepatitis C Virus AID - 10.3899/jrheum.090189 DP - 2009 Sep 01 TA - The Journal of Rheumatology PG - 1956--1957 VI - 36 IP - 9 4099 - http://www.jrheum.org/content/36/9/1956.short 4100 - http://www.jrheum.org/content/36/9/1956.full SO - J Rheumatol2009 Sep 01; 36 AB - Objective. To determine whether a mixed cryoglobulin type correlated with cirrhosis in patients infected with hepatitis C virus (HCV). Methods. We investigated the results of mixed cryoglobulin tests performed in the clinical laboratory on patients with and without HCV infection. Results. A higher prevalence of oligoclonal cryoglobulins designated Type IIa was present in HCV-infected patients with cirrhosis than in those without cirrhosis. Conclusion. An association of Type IIa cryoglobulins with cirrhosis in HCV-infected patients has not previously been reported.