RT Journal Article
SR Electronic
T1 Evaluation of Selected Rheumatoid Arthritis Activity Scores for Office-based Assessment
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2466
OP 2468
DO 10.3899/jrheum.091349
VO 37
IS 12
A1 MARY BETH SULLIVAN
A1 CHRISTINE IANNACCONE
A1 JING CUI
A1 BING LU
A1 KERRI BATRA
A1 MICHAEL WEINBLATT
A1 NANCY A. SHADICK
YR 2010
UL http://www.jrheum.org/content/37/12/2466.abstract
AB Objective. Patient-reported measures can quickly provide assessments of rheumatoid arthritis (RA) disease activity in the office setting and do not require a laboratory test or physician examination. The goal of our study was to establish the validity of patient-reported indices compared to the C-reactive protein-based Disease Activity Score (DAS28-CRP4). Methods. Baseline and 1-year followup DAS28-CRP4 data were obtained from 740 RA subjects and were compared to indices (MDHAQ, CDAI, RAPID, RADAI, GAS) according to cyclic citrullinated peptide (CCP) status and change at 1 year. Pairwise correlations were calculated for each index. Results. Among 740 subjects, mean age 57 years, disease duration 14 years, the CDAI (r = 0.84, Δ r = 0.80) and RAPID (r = 0.71, Δ r = 0.70) had the highest correlation with the DAS28-CRP4 scores at baseline and 1 year. These correlations were not influenced by CCP status, disease-modifying antirheumatic drug use, biologic use, or by disease duration. Conclusion. In RA, the CDAI and RAPID correlated well with the DAS28-CRP4. They may both be practical and informative in the care of patients in the office setting.