RT Journal Article
SR Electronic
T1 Testing an OMERACT MRI Scoring System for Peripheral Psoriatic Arthritis in Cross-sectional and Longitudinal Settings
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1811
OP 1815
DO 10.3899/jrheum.090351
VO 36
IS 8
A1 FIONA McQUEEN
A1 MARISSA LASSERE
A1 ANNE DUER-JENSEN
A1 CHARLOTTE WIELL
A1 PHILIP G. CONAGHAN
A1 FRÉDÉRIQUE GANDJBAKHCH
A1 KAY-GEERT A. HERMANN
A1 PAUL BIRD
A1 PERNILLE BØYESEN
A1 CHARLES PETERFY
A1 BO EJBJERG
A1 ESPEN A. HAAVARDSHOLM
A1 LAURA COATES
A1 MIKKEL ØSTERGAARD
YR 2009
UL http://www.jrheum.org/content/36/8/1811.abstract
AB Objective. Magnetic resonance imaging (MRI) is increasingly used to measure articular inflammation and damage in patients with psoriatic arthritis (PsA). We evaluated the reliability of a new OMERACT PsA MRI scoring system, PsAMRIS, in PsA fingers. Methods. In 2 separate studies, MRI scans were obtained from patients with clinical evidence of synovitis or dactylitis of the fingers. For the first cross-sectional study, images were obtained at one timepoint. For the second longitudinal study, images were obtained at 2 timepoints, 6 weeks apart. Scans were scored using PsAMRIS in an international multireader setting, for synovitis, tenosynovitis, periarticular inflammation, bone edema, bone erosions, and bone proliferation. Results. Global status scores from both datasets revealed moderate to high reliability for scoring most features, although reliability was poor for periarticular inflammation in the cross-sectional study. Change scores that reflected inflammatory activity also exhibited moderate to good reliability in the longitudinal exercise, despite there being very little absolute change in MRI synovitis or tenosynovitis observed in this dataset. At the distal interphalangeal joints, reliability for change scores was acceptable only for synovitis and tenosynovitis. Conclusion. Further development and testing of the PsAMRIS is planned to improve its performance as a clinical and research tool to identify and measure pathology in peripheral joint PsA.