RT Journal Article SR Electronic T1 Autologous Hematopoietic Stem Cell Transplant in Systemic Sclerosis: Quantitative High Resolution Computed Tomography of the Chest Scoring JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 1460 OP 1463 DO 10.3899/jrheum.081212 VO 36 IS 7 A1 DAVID LAUNAY A1 ZORA MARJANOVIC A1 CEDRIC de BAZELAIRE A1 LAURA FLOREA A1 SARAH ZOHAR A1 HOMAH KESHTMAND A1 CHRISTOPHE DELIGNY A1 AXELLE de RAIGNIAC A1 ATHOL U. WELLS A1 DOMINIQUE FARGE YR 2009 UL http://www.jrheum.org/content/36/7/1460.abstract AB Objective. Using high resolution computed tomography (HRCT), to assess the lung involvement outcome after autologous hematopoietic stem cell transplant (AHSCT) in patients with scleroderma (systemic sclerosis, SSc). Methods. HCRT scans prospectively performed before (n = 9 patients) and after (n = 47) AHSCT were blindly reviewed by 2 independent investigators using the Wells score. Results. After a median 60 months’ followup, the overall disease extent score from HCRT scans decreased from 10 (0–45) to 4 (0–36) (p = 0.04) 6 months after AHSCT, and thereafter increased up to 36 months and stabilized; the modified Rodnan skin score fell (p < 0.05). Conclusion. The extent of SSc lung involvement on HRCT rapidly but transiently regressed after AHSCT.