RT Journal Article
SR Electronic
T1 Symptoms of Depression Predict the Trajectory of Pain Among Patients with Early Inflammatory Arthritis: A Path Analysis Approach to Assessing Change
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 231
OP 239
DO 10.3899/jrheum.080147
VO 36
IS 2
A1 ORIT SCHIEIR
A1 BRETT D. THOMBS
A1 MARIE HUDSON
A1 SUZANNE TAILLEFER
A1 RUSSELL STEELE
A1 LAEORA BERKSON
A1 CAROLE BERTRAND
A1 FRANCOIS COUTURE
A1 MARY-ANN FITZCHARLES
A1 MICHEL GAGNÉ
A1 BRUCE GARFIELD
A1 ANDRZEJ GUTKOWSKI
A1 HARB KANG
A1 MORTON KAPUSTA
A1 SOPHIE LIGIER
A1 JEAN-PIERRE MATHIEU
A1 HENRI MÉNARD
A1 SUZANNE MERCILLE
A1 MICHAEL STARR
A1 MICHAEL STEIN
A1 MICHEL ZUMMER
A1 MURRAY BARON
YR 2009
UL http://www.jrheum.org/content/36/2/231.abstract
AB Objective. To assess the longitudinal relationships, including directionality, among chronic pain, symptoms of depression, and disease activity in patients with early inflammatory arthritis (EIA). Methods. One hundred eighty patients with EIA completed an examination, including swollen joint count, and were administered the Center for Epidemiological Studies Depression Scale (CES-D) and the McGill Pain Questionnaire (MPQ) at 2 timepoints 6 months apart. Cross-lagged panel path analysis was used to simultaneously assess concurrent and longitudinal relationships among pain, symptoms of depression, and number of swollen joints. Results. Pain, symptoms of depression, and number of swollen joints decreased over time (p < 0.001) and were prospectively linked to pain, symptoms of depression, and number of swollen joints, respectively, at 6 months. Symptoms of depression and pain were correlated with each other at baseline (0.47) and at 6-month followup assessments (0.28). Baseline symptoms of depression significantly predicted pain symptoms at 6 months (standardized regression coefficient = 0.28, p = 0.001), whereas pain and disease activity did not predict the course of any other variable after controlling for baseline values. Conclusion. Symptoms of depression predicted the trajectory of pain from baseline to 6 months. In addition, there were reciprocal/bidirectional associations between pain and symptoms of depression over time. More research is needed to better understand the relationship between pain and depressive symptoms and how to best manage patients with EIA who have high levels of both.