RT Journal Article
SR Electronic
T1 Pattern of Disease Onset, Diagnostic Delay, and Clinical Features in Juvenile Onset and Adult Onset Ankylosing Spondylitis
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2830
OP 2833
DO 10.3899/jrheum.090435
VO 36
IS 12
A1 SALIH OZGOCMEN
A1 OZGE ARDICOGLU
A1 AYHAN KAMANLI
A1 ARZU KAYA
A1 BEKIR DURMUS
A1 KADIR YILDIRIM
A1 OZLEM BAYSAL
A1 ALI GUR
A1 SALIHA KARATAY
A1 ZUHAL ALTAY
A1 REMZI CEVIK
A1 AKIN ERDAL
A1 YUKSEL ERSOY
A1 AYSEGUL J. SARAC
A1 IBRAHIM TEKEOGLU
A1 MAHIR UGUR
A1 KEMAL NAS
A1 KAZIM SENEL
A1 HASAN ULUSOY
YR 2009
UL http://www.jrheum.org/content/36/12/2830.abstract
AB Objective. To assess the frequency of juvenile onset ankylosing spondylitis (JOAS) in Turkish patients with AS and to compare with adult onset AS (AOAS) in a cross-sectional study design.Methods. A total of 322 patients were recruited from the joint database of 5 university hospitals in eastern Turkey.Results. Patients with JOAS (n = 43, 13.4%) had significantly longer diagnostic delay (9.21 vs 5.08 yrs), less severe axial involvement and more prevalent uveitis (OR 2.92, 95% CI 1.25–6.79), and peripheral involvement at onset (OR 3.25, 95% CI 1.51–6.98, adjusted for current age; and OR 2.26, 95% CI 1.07–4.76, adjusted for disease duration). Patients with AOAS had higher radiographic scores and more restricted clinimetrics but similar functional limitations and quality of life.Conclusion. JOAS and AOAS had distinctive courses and Turkish patients with AS had similar features compared to other Caucasian patient populations.