PT  - JOURNAL ARTICLE
AU  - IL-HOON SUNG
AU  - TAE-HWAN KIM
AU  - SO-YOUNG BANG
AU  - TAE-JONG KIM
AU  - BITNARA LEE
AU  - LYNETTE PEDDLE
AU  - PROTON RAHMAN
AU  - CELIA M.T. GREENWOOD
AU  - PINGZHAO HU
AU  - ROBERT D. INMAN
TI  - IL-23R Polymorphisms in Patients with Ankylosing Spondylitis in Korea
AID  - 10.3899/jrheum.081121
DP  - 2009 May 01
TA  - The Journal of Rheumatology
PG  - 1003--1005
VI  - 36
IP  - 5
4099  - http://www.jrheum.org/content/36/5/1003.short
4100  - http://www.jrheum.org/content/36/5/1003.full
SO  - J Rheumatol2009 May 01; 36
AB  - Objective. IL23R polymorphisms have been shown to have a significant association with ankylosing spondylitis (AS). To date, these studies have been restricted to Caucasian patients with AS. Our study addresses this relationship in Korean patients with AS. Methods. A total of 451 patients with AS and 392 ethnically matched healthy controls were enrolled. All patients were native Koreans with AS satisfying the modified New York criteria. In total, 10 single nucleotide polymorphisms (SNP) within the IL-23R gene cluster were genotyped. Results. No IL-23R SNP were found to be associated with AS in Koreans. Conclusion. The association of IL23R and AS that is seen in Caucasian patients with AS is not present in Korean patients with AS.