RT Journal Article
SR Electronic
T1 Dietary and Lifestyle Changes Associated with High Prevalence of Hyperuricemia and Gout in the Shandong Coastal Cities of Eastern China
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1859
OP 1864
VO 35
IS 9
A1 ZHIMIN MIAO
A1 CHANGGUI LI
A1 YING CHEN
A1 SHIHUA ZHAO
A1 YANGANG WANG
A1 ZHONGCHAO WANG
A1 XINYAN CHEN
A1 FENG XU
A1 FANG WANG
A1 RUIXIA SUN
A1 JIANXIA HU
A1 WEI SONG
A1 SHENGLI YAN
A1 CONG-YI WANG
YR 2008
UL http://www.jrheum.org/content/35/9/1859.abstract
AB Objective To demonstrate the prevalence of hyperuricemia and gout associated with dietary and lifestyle changes and evaluate the implication of metabolic disorders to the development of hyperuricemia. Methods Data collected from 5,003 subjects randomly recruited from 5 coastal cities (Qingdao, Rizhao, Yantai, Weihai, and Dongying) of Shandong province in Eastern China were analyzed. Results Overall, the prevalence for hyperuricemia and gout in the studied populations was 13.19% and 1.14%, respectively. The prevalence was significantly higher in men as compared to women (18.32% vs 8.56% for hyperuricemia, 1.94% vs 0.42% for gout). Hyperuricemia was more common in men over age 30 and in women over age 50. A significant steady increase for the prevalence was noted as compared to the previous published data. Urban residents showed much higher prevalence of hyperuricemia as compared to rural residents (14.9% vs 10.1%, p = 0.004). Similarly, higher prevalence was noted in the developed city compared to the less developed city (18.02 vs 5.3%). These discrepancies were highly correlated with economic development as manifested by the increase of daily consumption of meat and seafood. Additionally, alcohol, overweight or obesity, hypertension, and abnormal triglycerides were highly associated with higher prevalence of hyperuricemia. Moreover, hyperuricemia is likely a risk factor for the development of diabetes mellitus. Conclusion There was a remarkable increase for the prevalence of hyperuricemia and gout, which is highly correlated with the development of the economy as manifested by dietary and lifestyle changes.