PT  - JOURNAL ARTICLE
AU  - LAURA TRUPIN
AU  - M. CHRISTINE TONNER
AU  - JINOOS YAZDANY
AU  - LAURA J. JULIAN
AU  - LINDSEY A. CRISWELL
AU  - PATRICIA P. KATZ
AU  - EDWARD YELIN
TI  - The Role of Neighborhood and Individual Socioeconomic Status in Outcomes of Systemic Lupus Erythematosus
DP  - 2008 Sep 01
TA  - The Journal of Rheumatology
PG  - 1782--1788
VI  - 35
IP  - 9
4099  - http://www.jrheum.org/content/35/9/1782.short
4100  - http://www.jrheum.org/content/35/9/1782.full
SO  - J Rheumatol2008 Sep 01; 35
AB  - Objective To determine if neighborhood socioeconomic status (SES) is independently related to physical and mental health outcomes in systemic lupus erythematosus (SLE). Methods Data derived from the first 3 waves of the Lupus Outcomes Study, a telephone survey of 957 patients with confirmed SLE diagnoses, recruited from clinical and non-clinical sources. Residential addresses were geocoded to U.S. Census block groups. Outcome measures included the Systemic Lupus Activity Questionnaire (SLAQ) score, a self-reported assessment of SLE symptoms; the Medical Outcomes Study Short Form-36 Health Survey physical functioning score; and Center for Epidemiologic Studies-Depression (CES-D) score of ≥ 19 points. Multivariate analyses adjusted for race/ethnicity and other demographic and health-related covariates. Results After adjustment, lower individual SES, measured by education, household income, or poverty status, was associated with all outcomes. In models that did not include individual SES, low neighborhood SES (> 30% of residents in poverty) was also associated with poor outcomes. After adjustment for individual SES, demographic, and health-related covariates, only CES-D ≥ 19 remained associated with neighborhood SES: 47% [95% confidence interval (CI) 38–56%] versus 35% (95% CI 32–37%). Conclusion Individual SES is associated with physical and mental health outcomes in persons with SLE. Low neighborhood SES contributes independently to high levels of depressive symptoms. Future research should focus on mechanisms underlying these differences. (First Release July 15 2008; J Rheumatol 2008;35:1782–8)