TY - JOUR T1 - Osteoarthritis: A Companion to Rheumatology JF - The Journal of Rheumatology JO - J Rheumatol SP - 1232 LP - 1232 VL - 35 IS - 6 AU - Veerapong Phumethum AU - Peter Lee Y1 - 2008/06/01 UR - http://www.jrheum.org/content/35/6/1232.abstract N2 - Leena Sharma and Francis Berenbaum, editors, Philadelphia: Mosby, Inc., 2007, 279 pages, US $129.00. This “Companion to Rheumatology” on osteoarthritis (OA) is a detailed, up-to-date review on the epidemiology, pathogenesis, and radiological, clinical and treatment perspectives of the disorder, written by an international cast of leaders in their fields. The chapters on pathogenesis provide an excellent discussion on the role of changes in the subchondral bone, chondrocytes, and adipokines (especially leptins) in OA. A section on biochemical markers and discussion on predictors and measurement of disease progression are particularly relevant. The chapter on management is comprehensive and appropriately includes a… ER -