TY - JOUR T1 - Cutaneous mastocytosis in a patient with primary Sjögren's syndrome. JF - The Journal of Rheumatology JO - J Rheumatol SP - 1697 LP - 1700 VL - 33 IS - 8 AU - Shebnem Kalay Erbay AU - Carol Stewart AU - Ashraf Hassanein AU - Andrew Fletcher AU - Indraneel Bhattacharyya AU - Donald Cohen AU - Stanton K Wesson AU - Jason Weinstein AU - Robert Lyons AU - Westley H Reeves Y1 - 2006/08/01 UR - http://www.jrheum.org/content/33/8/1697.abstract N2 - Mast cells have been linked to rheumatoid arthritis (RA) and are essential to the pathogenesis of RA-like disease in a mouse model. We describe a 34-year-old woman who developed Sjögren's syndrome concurrently with telangiectasia macularis eruptiva perstans (TMEP), a rare form of cutaneous mastocytosis. The patient had sicca symptoms with an abnormal minor salivary gland biopsy and decreased salivary flow, peripheral neuropathy, an 80 pound weight loss, and a macular erythematous rash that exhibited superficial perivascular mast cell infiltrates on biopsy of lesional skin. This case further underscores the link between mast cells and the development of autoimmunity. ER -