PT  - JOURNAL ARTICLE
AU  - Shebnem Kalay Erbay
AU  - Carol Stewart
AU  - Ashraf Hassanein
AU  - Andrew Fletcher
AU  - Indraneel Bhattacharyya
AU  - Donald Cohen
AU  - Stanton K Wesson
AU  - Jason Weinstein
AU  - Robert Lyons
AU  - Westley H Reeves
TI  - Cutaneous mastocytosis in a patient with primary Sjögren's syndrome.
DP  - 2006 Aug 01
TA  - The Journal of Rheumatology
PG  - 1697--1700
VI  - 33
IP  - 8
4099  - http://www.jrheum.org/content/33/8/1697.short
4100  - http://www.jrheum.org/content/33/8/1697.full
SO  - J Rheumatol2006 Aug 01; 33
AB  - Mast cells have been linked to rheumatoid arthritis (RA) and are essential to the pathogenesis of RA-like disease in a mouse model. We describe a 34-year-old woman who developed Sjögren's syndrome concurrently with telangiectasia macularis eruptiva perstans (TMEP), a rare form of cutaneous mastocytosis. The patient had sicca symptoms with an abnormal minor salivary gland biopsy and decreased salivary flow, peripheral neuropathy, an 80 pound weight loss, and a macular erythematous rash that exhibited superficial perivascular mast cell infiltrates on biopsy of lesional skin. This case further underscores the link between mast cells and the development of autoimmunity.